Control-Option-Command-Delete no longer works under Monterey

I think this is indeed a Monterey thing (rather than anything to do with Keyboard Maestro) as I've just tested and this key ⌃⌥⌘⌫ combination cannot now be set in the App, Better Touch Tool either.
macOS: 12.3.1 (Monterey)
KM Version: 10.1.1