First -- have a read of this thread, paying particular attention to @peternlewis's posts, and decide whether you want to "deactivate" or "disable" the Groups.
Then decide whether you are happy to have the KM Editor open to do this (I have it running all the time so it wouldn't matter to me, other people quit the Editor when not editing macros) -- how you get the Group names will depend on this.
Or are you happy to maintain a hard-coded list of Groups to change, rather than programmatically getting "every Group whose name starts with •"?