Possible for Notification windows to trigger macro?

Wondering if its possible for a Notification window to trigger a macro?

Use case: Detect incoming iPhone based call and display the caller in Contacts if they are known. Also, log the call’s start and end time (duration of iPhone call notification window) to a log file for time sheet purposes. Similar use case for outgoing calls (show contact, log call’s time based on duration of notification window).

Use case: Detect an incoming iMessage and ignore or respond to it in the background, or activate Messages app … depending on the sender.

No. At least no way I know of, and I highly doubt Apple will ever add an API to support this.