This is just a short post to serve as a useful point of reference for those who are wanting to impose this precise functionality. For those people are typing documents in a language like LaTeX, an important functionality is inverse-search, i.e. clicking on a PDF document generated, usually in a reader like Skim on macOS, which then cycles to the location in the terminal where you're editing the file.
The problem is that in Skim, this requires the shortcut Cmd + Shift + Click.
People have asked for a feature request so that inverse searching can be done entirely with the mouse.
I set this up in Keyboard Maestro with the following:
Basically just a simple mouse click with modifier mapped to a keystroke. Then in a program like Better Mouse (or any mouse management program) you can then associate that keystroke to a mouse button.