In my experience, yes. On Mac and iOS.
Same with AdBlock for YouTube.
Same with uBlock.
My wife and I have been using this for a couple of years with great success.
Youtube Ad Skipper.kmmacros (4.1 KB)
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Hey Chris - what's the Don't Rotate Status Menu action?
That’s a nifty little action that is “hidden”, but prevents the menu bar icon from animating. Since it’s hidden, I have it saved as a favorite to easily add it. It’s handy for macros that trigger very frequently, or that have long pauses etc.
See this comment by Peter for more info. 
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Got it! Thanks Chris 
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If you only use YouTube on browser ad blocker is the way to go
If you wanna use it on Apple TV or iPhone I suggest just get YouTube red you can share with 5 more people too
If you have an Android/Google TV, SmartTubeNext is brilliant and you can customise pretty much everything.
Thanks man !
but … it doesn't work.
after I put this macros into Global Macro Group, it works now.
I found it failed when different language input method is not corresponding to the current video loaded. I need to switch the matching method to make it resume 
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Glad you got it going!
Thank you very much !
it works fine now, I don't even need to care about the input methods anymore … really no idea what's going on.
I was afraid that this Macros repeating itself every seconds which might consume some CPU processes and I tried to test it with different repeating time like 5 seconds, but the fact is that nothing really gets delayed. and I also find it won't perform this action when the window is not focused. so my worries about it might hinder the normal use of other applications is totally futile.
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Glad to help. Since there were several different recommendations in this post, for posterity’s sake, feel free to mark whichever one works best for you as the solution.
Yes of course, thanks everybody !
you all widen my considerations
I haven't seen a YouTube ad in years, but it never occurred to me to look for a technical solution. I simply upgraded to YouTube Premium. Part of me hopes that the creators get a bit of a kickback as well.
how much you need to pay for the Premium ? every month ?
Same experience here: Brave does it all.
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As with most subscriptions, YouTube Premium has raised its prices significantly in the past few years. We currently pay $23 / month for the Family Plan. (It was $14.99 / month not too long ago.)
Three of us share the family plan. All three of us watch a fair number of YouTube videos, so that equates to $7.67 / month / person. Google allows for up to five shared email addresses on the family plan. Each user gets their own profile — with their own favorites, subscriptions, playlists, and recommendations.
The individual plan is only $13.99 and you get 2 months free if you pay annually. I'm not trying to shill for Google. I just hate ads and only patronize platforms where I can get ad-free content.
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Thanks !
