Mapping a Keyboard Maestro Macro to a Logitech Mouse Button?

really, hmm that´s strange. i can try a different keyboard and mouse but as you said it shouldnt make a difference.
i have a somehow similar problem where shift and streamdeck triggers not getting tracked correctly:

@peternlewis, i wonder if this both happens due to a odd system/keybaord maestro constellation/configuration?

Iam grateful for any hint.