So suddenly all the Keystrokes cause a beep and no macro is executed

It’s a mystery!

Running El Capitan on a 2012 (I think) MacBook Pro. I didn’t install any new software or upgrade or nothin’!

Thanks…

Clearly something changed. Think carefully. Review your Mac App Store, and other apps for auto-updates.

Of course, you have done a restart of your Mac, right?

Check your recently run macros to see if anything unexpected is there:

Please post the versions of KM and macOS you are running.