That’s definitely not a “duh” moment, I’ve had KM for years and still do the same thing sometimes... and then stare at the screen and wonder what’s broken.
I hope you don't mind that I have revised your topic title to better reflect the question you have asked.
FROM: I am embarrassed to ask
TO: Why Does Macro Not Run Using HotKey, But Does Run from KM Editor?
This will greatly help you attract more experienced users to help solve your problem, and will help future readers find your question, and the solution.
Don't worry about being embarrassed or asking what you may think is a simple or obvious question. Chances are if you have the question, others do as well.
It is always best to give your Topic a Title that is descriptive of your question or issue.