Yes, see:
Continuing the discussion from Ready for Mojave :
Wiki Post on Resolving Mojave Issues
UPDATED: 2019-09-02 16:53 GMT-5
** First, see this KM Wiki Article:**
Accessibility Permission Problems (Mojave & Catalina)
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In addition to the suggestions made by Peter @peternlewis in the above announcement, you might consider the following:
You will have to ensure you enable Accessibility for both Keyboard Maestro and Keyboard Maestr…
and specifically:
Yes, simulated keys that are hot keys of the system or other applications, that use arrows or function keys apparently don't trigger the hot keys in Mojave.
I have reported this to Apple (and done all the hard work of providing them with a test application). No idea if they will resolve it, for all I know they think this is a security feature.
This bug has been reported to Apple, together with an application to demonstrate the issue. Who knows if they will fix it. One solution is to change the hot key to toggle DND to something that does not use the function keys and thus can be simulated.